Title

Drosophila larvae show effects on development and survival after ingestion of Pseudomonas fluorescens

Date

5-28-2015 2:00 PM

End Time

28-5-2015 4:00 PM

Location

Werner University Center (WUC) Pacific Room

Department

Biology

Session Chair

Ava Howard

Session Chair

Jeffrey Snyder

Session Title

Research in the Biological Sciences

Faculty Sponsor(s)

Kristin Latham

Presentation Type

Poster session

Abstract

Drosophila melanogaster, the fruit fly, is a model organism with genetic applications and an accelerated life cycle, making them an ideal subject for developmental and immune system research. There has been little research investigating the lethal and non-lethal responses of flies infected with bacteria early in development. To further the knowledge on the early developmental responses of their immune system, this study examines flies that were exposed to wild type and mutant strains of P. fluorescens at the larval stage. In this study it was hypothesized that the bacteria would cause severe delays coupled with high mortality. First to second instar larvae were fed the strains Pf-5, A506 and SWB25 in one dose and then observed through the rest of development. It was found that both developmental delay (varying in degree) and lethality was observed in some of the flies exposed depending on the strain of bacteria. In further applications, this research could give insight to the innate immune response exhibited in humans to bacterial infections.

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May 28th, 2:00 PM May 28th, 4:00 PM

Drosophila larvae show effects on development and survival after ingestion of Pseudomonas fluorescens

Werner University Center (WUC) Pacific Room

Drosophila melanogaster, the fruit fly, is a model organism with genetic applications and an accelerated life cycle, making them an ideal subject for developmental and immune system research. There has been little research investigating the lethal and non-lethal responses of flies infected with bacteria early in development. To further the knowledge on the early developmental responses of their immune system, this study examines flies that were exposed to wild type and mutant strains of P. fluorescens at the larval stage. In this study it was hypothesized that the bacteria would cause severe delays coupled with high mortality. First to second instar larvae were fed the strains Pf-5, A506 and SWB25 in one dose and then observed through the rest of development. It was found that both developmental delay (varying in degree) and lethality was observed in some of the flies exposed depending on the strain of bacteria. In further applications, this research could give insight to the innate immune response exhibited in humans to bacterial infections.