Title

Superantigens; Super Deadly

Date

5-28-2015 9:00 AM

End Time

28-5-2015 11:00 AM

Location

Werner University Center (WUC) Pacific Room

Department

Chemistry

Session Chair

Patricia Flatt

Session Title

Deadly Toxins: Who Makes Them and How Do They Work?

Faculty Sponsor(s)

Patricia Flatt

Presentation Type

Poster session

Abstract

We’ve all heard of Superbugs but have you heard of Superantigens? Antigens are usually foreign substances that elicit an immune response. However, some microbes produce Superantigens that cause a dangerous overreaction by the T-helper cells of the immune system. Staphylococcus aureus is a bacterium that is capable of producing several different Superantigens. These include toxic shock syndrome toxin, exfoliating toxin A and B, and enterotoxins A, B, C, D, and E. By over activating your T-cells, these Superantigens can cause many different symptoms which can lead to multiple organ failure and death.

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May 28th, 9:00 AM May 28th, 11:00 AM

Superantigens; Super Deadly

Werner University Center (WUC) Pacific Room

We’ve all heard of Superbugs but have you heard of Superantigens? Antigens are usually foreign substances that elicit an immune response. However, some microbes produce Superantigens that cause a dangerous overreaction by the T-helper cells of the immune system. Staphylococcus aureus is a bacterium that is capable of producing several different Superantigens. These include toxic shock syndrome toxin, exfoliating toxin A and B, and enterotoxins A, B, C, D, and E. By over activating your T-cells, these Superantigens can cause many different symptoms which can lead to multiple organ failure and death.